SCHEMBL4469770

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4465612	0.87	HRH3 (0.59)	HRH3TNKSSMN1; SMN2NPC1RAB9A
	SCHEMBL4477687	0.87	CNR2 (0.63)	HRH3TNKSSMN1; SMN2CNR2NPC1
	SCHEMBL24061141	0.83	HRH3 (0.82)	HRH3SMN1; SMN2NPC1RAB9ANOS3
	SCHEMBL11864	0.81	HRH3 (0.71)	HRH3SMN1; SMN2NOS3NOS1NOS2
	SCHEMBL26371010	0.81	HRH3 (0.72)	HRH3TNKSSMN1; SMN2NPC1RAB9A
	SCHEMBL14791028	0.80	HRH3 (0.69)	HRH3SMN1; SMN2NOS3NOS1NOS2
	SCHEMBL14787825	0.80	HRH3 (0.69)	HRH3SMN1; SMN2NOS3NOS1NOS2
	SCHEMBL13161945	0.79	HRH3 (0.62)	HRH3TNKSSMN1; SMN2NPC1RAB9A
	SCHEMBL13376445	0.78	HRH3 (0.68)	HRH3TNKSSMN1; SMN2NPC1RAB9A
	SCHEMBL4489047	0.78	AGTR1 (0.50)	HRH3SMN1; SMN2CNR2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.