Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2642488 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2NOS1HSD17B10GABRA5GABRB2 | |
| SCHEMBL2645321 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2NOS1HSD17B10GABRA5GABRB2 | |
| SCHEMBL23170681 | 0.74 | HPGD (0.38) | SMN1; SMN2ALDH1A1KDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL27514793 | 0.72 | HPGD (0.37) | SMN1; SMN2ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL11656088 | 0.70 | LTA4H (0.61) | SMN1; SMN2NOS1HSD17B10LTA4HMKNK1 | |
| SCHEMBL11656085 | 0.67 | HSD17B10 (0.54) | SMN1; SMN2HSD17B10LTA4HMKNK1MKNK2 | |
| SCHEMBL28185226 | 0.67 | HDAC1 (0.49) | SMN1; SMN2ALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL10719025 | 0.65 | ALDH1A1 (0.61) | SMN1; SMN2NOS1HSD17B10LTA4HMKNK1 | |
| SCHEMBL7026518 | 0.64 | SMN1; SMN2 (0.75) | SMN1; SMN2NOS1HSD17B10GABRA5GABRB2 | |
| SCHEMBL461605 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569375-B1 | MODIFIED PIGMENTS | CABOT CORP (US) | 2017-11-22 | — | — | EP | disclosed |
| US-8771411-B2 | Modified pigments | CABOT CORPORATION (US) | 2014-07-08 | — | — | US | disclosed |
| EP-2569375-A2 | MODIFIED PIGMENTS | Cabot Corporation (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20130061773-A1 | MODIFIED PIGMENTS | CABOT CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2011143533-A2 | MODIFIED PIGMENTS | CABOT CORPORATION (US) | 2011-11-17 | — | — | WO | disclosed |
| EP-0048538-A1 | Azo dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-31 | — | — | EP | disclosed |