Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 19/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19331228 | 0.92 | PHGDH (0.57) | PHGDHPOLB | |
| SCHEMBL26373372 | 0.91 | PHGDH (0.47) | PHGDHPOLB | |
| SCHEMBL19343245 | 0.85 | PHGDH (0.54) | PHGDHPOLB | |
| SCHEMBL26373359 | 0.83 | PHGDH (0.42) | PHGDH | |
| SCHEMBL19343376 | 0.83 | PHGDH (0.55) | PHGDHPOLB | |
| SCHEMBL26373365 | 0.82 | PHGDH (0.42) | PHGDHPOLB | |
| SCHEMBL26373367 | 0.81 | PHGDH (0.42) | PHGDHPOLB | |
| SCHEMBL23851658 | 0.79 | PHGDH (0.56) | PHGDHPOLB | |
| SCHEMBL19342154 | 0.76 | PHGDH (0.59) | PHGDHPOLB | |
| SCHEMBL19343644 | 0.76 | PHGDH (0.67) | PHGDHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312536-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312536-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | PHGDH, G6PD, PGD | PHGDH 1/4885POLB 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.