Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637340 | 1.00 | ERN1 (0.52) | ERN1APPMAPTALDH1A1CYP1A1 | |
| SCHEMBL2637738 | 0.85 | CYP19A1 (0.62) | APPMAPTCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL2637736 | 0.85 | CYP19A1 (0.62) | APPMAPTCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL4258547 | 0.84 | CYP1A1 (0.62) | APPMAPTALDH1A1CYP1A1CYP1B1 | |
| SCHEMBL4258548 | 0.84 | CYP1A1 (0.62) | APPMAPTALDH1A1CYP1A1CYP1B1 | |
| SCHEMBL10477813 | 0.84 | ALDH1A1 (0.58) | ERN1MAPTALDH1A1PTGS2SMN1; SMN2 | |
| SCHEMBL7090237 | 0.81 | TUBB4A (0.51) | MAPTALDH1A1CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL13059995 | 0.80 | MAPT (0.55) | APPMAPTALDH1A1CYP1A1CYP1B1 | |
| SCHEMBL2637083 | 0.79 | MAPT (0.51) | APPMAPTALDH1A1CYP1A1CYP1B1 | |
| SCHEMBL2637081 | 0.79 | MAPT (0.51) | APPMAPTALDH1A1CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2437792-B1 | IMAGING OF MYELIN BASIC PROTEIN | GEN ELECTRIC (US) | 2015-10-21 | — | — | EP | disclosed |
| EP-2437792-A2 | IMAGING OF MYELIN BASIC PROTEIN | General Electric Company (US) | 2012-04-11 | — | — | EP | disclosed |
| US-20100310456-A1 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| WO-2010141704-A2 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310456-A1 | IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | ERN1 2631/4885APP 1205/4885MAPT 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.