SCHEMBL24910307

SCHEMBL24910307

CC(C)c1nc2c(C(F)(F)F)cccc2o1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 3/20 0.36
P2RX7 Q99572 1/20 0.36
EPHX2 P34913 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
PARP1 P09874 1/20 0.33
TRPA1 O75762 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
NOTUM Q6P988 1/20 0.33
TP53 P04637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ELANE P08246 1/20 0.32
MPO P05164 1/20 0.32
NCF1 P14598 1/20 0.31
ESR1 P03372 1/20 0.31
CYP1A2 P05177 1/20 0.31
GLA P06280 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13058470 0.79 DAGLA (0.37) HRH4NPC1RAB9ACHRNB2CHRNA4
SCHEMBL14610912 0.77 TP53 (0.42) TP53ELANE
SCHEMBL26375286 0.77 ELANE (0.42) HRH4PARP1NOTUMALDH1A1L3MBTL1
SCHEMBL31391540 0.76 HRH4 (0.38) HRH4EPHX2NPC1RAB9APARP1
SCHEMBL9905050 0.76 ACHE (0.39) RAB9ATP53ALDH1A1NCF1CYP1A2
SCHEMBL30237792 0.76 HRH4 (0.43) HRH4NPC1RAB9APARP1NOTUM
SCHEMBL19914338 0.76 HRH4 (0.38) HRH4P2RX7EPHX2NPC1RAB9A
SCHEMBL23479819 0.76 MAPT (0.42) HRH4NPC1RAB9APARP1CHRNB2
SCHEMBL19914341 0.76 HRH4 (0.38) HRH4EPHX2NPC1RAB9APARP1
SCHEMBL25488150 0.75 MTNR1A (0.43) P2RX7EPHX2PARP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122934-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-01-25 EP disclosed