SCHEMBL26375313

SCHEMBL26375313

Cc1cccc(-c2cc(F)c(F)c(F)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.48
RPS6KA3 P51812 1/20 0.44
PTPN5 P54829 1/20 0.42
RAB9A P51151 3/20 0.41
DHODH Q02127 1/20 0.41
AR P10275 1/20 0.41
AKR1C2 P52895 2/20 0.41
AKR1C3 P42330 1/20 0.41
NPC1 O15118 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TP53 P04637 1/20 0.40
AKR1C1 Q04828 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
ENPP3 O14638 1/20 0.40
IDO1 P14902 1/20 0.39
METAP2 P50579 1/20 0.39
NR3C1 P04150 1/20 0.39
PDK2 Q15119 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674923 0.87 ACHE (0.48) ACHERPS6KA3PTPN5RAB9ADHODH
SCHEMBL29674880 0.83 AKR1C2 (0.45) ACHERPS6KA3PTPN5RAB9ADHODH
SCHEMBL12225756 0.83 ACHE (0.48) ACHERPS6KA3PTPN5RAB9AAR
SCHEMBL20233098 0.83 ACHE (0.48) ACHEPTPN5RAB9ADHODHAR
SCHEMBL28043529 0.81 ACHE (0.61) ACHEPTPN5RAB9ADHODHAKR1C2
SCHEMBL30443064 0.81 ACHE (0.61) ACHEPTPN5RAB9ADHODHAKR1C2
SCHEMBL20763226 0.81 ACHE (0.46) ACHERPS6KA3PTPN5RAB9AAR
SCHEMBL29373699 0.81 ACHE (0.69) ACHEPTPN5RAB9ADHODHAR
SCHEMBL31471473 0.81 ACHE (0.69) ACHEPTPN5RAB9ADHODHAR
SCHEMBL301247 0.81 ACHE (0.69) ACHEPTPN5RAB9ADHODHAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 ACHE 1667/4885RPS6KA3 3916/4885PTPN5 4830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.