SCHEMBL28043529

SCHEMBL28043529

Cc1cccc(-c2cc(-c3cccc(C)c3)cc(-c3cccc(C)c3)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.61
DHODH Q02127 1/20 0.53
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP1A1 P04798 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2E1 P05181 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C8 P10632 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2A6 P11509 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP4B1 P13584 1/20 0.48
CYP2B6 P20813 1/20 0.48
CYP3A5 P20815 1/20 0.48
CYP2A7 P20853 1/20 0.48
CYP3A7 P24462 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30443064 1.00 ACHE (0.61) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL19577801 0.97 ACHE (0.65) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL29057032 0.95 ACHE (0.55) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL30493472 0.95 ACHE (0.55) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL29373699 0.94 ACHE (0.69) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL31471473 0.94 ACHE (0.69) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL301247 0.94 ACHE (0.69) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL28043537 0.92 TSHR (0.53) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL9419197 0.92 ACHE (0.67) ACHEDHODHRAB9ANPC1HPGD
SCHEMBL18797759 0.91 ACHE (0.65) ACHERAB9ANPC1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037072-B A kind of synthetic method of 1,3,5-triarylbenzenes compound 华侨大学 2016-11-30 CN disclosed
CN-105037072-A Synthetic method for 1,3,5-triarylbenzene compound UNIV HUAQIAO 2015-11-11 CN disclosed