SCHEMBL26375396

SCHEMBL26375396

Cc1ccc(-c2ccc(OC(F)(F)F)cc2)c(C(F)(F)F)c1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.53
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
PDE3B Q13370 2/20 0.42
PDE3A Q14432 2/20 0.42
SCN5A Q14524 5/20 0.42
FFAR4 Q5NUL3 1/20 0.41
S1PR1 P21453 2/20 0.40
RORC P51449 1/20 0.39
HCRTR1 O43613 1/20 0.39
HCRTR2 O43614 1/20 0.39
KIF11 P52732 1/20 0.39
SRD5A2 P31213 1/20 0.38
MGAT2 Q10469 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26375393 0.87 GPR3 (0.49) GPR3SCN5AFFAR4S1PR1HCRTR1
SCHEMBL22304413 0.86 AKR1C3 (0.55) AKR1C3AKR1C2PDE3BPDE3AS1PR1
SCHEMBL24297564 0.84 AKR1C3 (0.54) AKR1C3AKR1C2PDE3BPDE3AS1PR1
SCHEMBL19323000 0.84 AKR1C3 (0.58) AKR1C3AKR1C2PDE3BPDE3AS1PR1
SCHEMBL16727887 0.83 GPR3 (0.55) GPR3SCN5AFFAR4S1PR1RORC
SCHEMBL26375397 0.83 GPR3 (0.49) GPR3AKR1C3AKR1C2HCRTR1HCRTR2
SCHEMBL16728065 0.82 GPR3 (0.54) GPR3PDE3BPDE3ASCN5AFFAR4
SCHEMBL19993280 0.81 GPR3 (0.53) GPR3SCN5AFFAR4RORCKIF11
SCHEMBL9228178 0.81 GPR3 (0.53) GPR3PDE3BPDE3ASCN5AFFAR4
SCHEMBL1148978 0.81 GLA (0.59) GPR3AKR1C2PDE3BPDE3ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 GPR3 2866/4885AKR1C3 2808/4885AKR1C2 1775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.