SCHEMBL26375397

SCHEMBL26375397

Cc1ccc(-c2cccc(OC(F)(F)F)c2)c(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.49
PTGES2 Q9H7Z7 1/20 0.46
AKR1C4 P17516 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
HCRTR1 O43613 2/20 0.41
HCRTR2 O43614 2/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
PDE10A Q9Y233 1/20 0.41
KCNH2 Q12809 1/20 0.40
SCN10A Q9Y5Y9 1/20 0.40
XDH P47989 2/20 0.40
PIM1 P11309 2/20 0.39
PIM2 Q9P1W9 2/20 0.39
PRMT1 Q99873 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
SLC22A12 Q96S37 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26375396 0.83 GPR3 (0.53) GPR3AKR1C3AKR1C2HCRTR1HCRTR2
SCHEMBL278095 0.82 GPR3 (0.48) GPR3PTGES2ADORA2AADORA1PDE10A
SCHEMBL24910424 0.82 AKR1C3 (0.58) AKR1C4AKR1C3AKR1C2AKR1C1ADORA2A
SCHEMBL5542229 0.79 PTGES2 (0.50) GPR3PTGES2KCNH2SCN10AXDH
SCHEMBL26375380 0.78 PDE3B (0.51) AKR1C4AKR1C3AKR1C2AKR1C1HCRTR1
SCHEMBL26375430 0.78 NFE2L2 (0.45) AKR1C3AKR1C2ADORA2AADORA1PRMT1
SCHEMBL1044062 0.78 CYP1A2 (0.51) GPR3PTGES2KCNH2SCN10AXDH
SCHEMBL4637120 0.77 AKR1C3 (0.51) AKR1C3AKR1C2
SCHEMBL3378380 0.77 KIF11 (0.53) SLC22A12
SCHEMBL5542629 0.75 ADORA2A (0.47) GPR3ADORA2AADORA1KCNH2SCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 GPR3 2866/4885PTGES2 3880/4885AKR1C4 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.