SCHEMBL26375581

SCHEMBL26375581

Cc1cc(-c2c(F)c(F)c(C(F)(F)F)c(F)c2F)cc(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.41
IKBKB O14920 1/20 0.38
RAPGEF4 Q8WZA2 2/20 0.35
RXRA P19793 4/20 0.34
RXRB P28702 4/20 0.34
RXRG P48443 2/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
NFE2L2 Q16236 1/20 0.30
TAS2R14 Q9NYV8 1/20 0.30
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17570537 0.91 NOTUM (0.44) NOTUMIKBKBRAPGEF4RXRARXRB
SCHEMBL26375583 0.81 NOTUM (0.43) NOTUMIKBKBRAPGEF4
SCHEMBL26375464 0.80 NOTUM (0.50) NOTUMIKBKBRAPGEF4RXRARXRB
SCHEMBL12583213 0.80 NOTUM (0.50) NOTUMIKBKBRAPGEF4RXRARXRB
SCHEMBL26568307 0.79 IKBKB (0.37) NOTUMIKBKBRAPGEF4RXRARXRB
SCHEMBL24254767 0.79 IKBKB (0.41) NOTUMIKBKBRAPGEF4RXRARXRB
SCHEMBL13949153 0.78 NOTUM (0.49) NOTUMIKBKBRAPGEF4RXRARXRB
SCHEMBL24910428 0.78 PTPN5 (0.33) IKBKB
SCHEMBL26375568 0.77 ENPP1 (0.37)
SCHEMBL13170619 0.77 RXRA (0.47) NOTUMRAPGEF4RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 NOTUM 2913/4885IKBKB 4682/4885RAPGEF4 2769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.