SCHEMBL26375747

SCHEMBL26375747

c1ccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-c3nc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5cc(-n6c7ccccc7c7ccccc76)ccc54)n3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
RAC2 P15153 1/20 0.34
RAC3 P60763 1/20 0.34
CDC42 P60953 1/20 0.34
RAC1 P63000 1/20 0.34
PTPN1 P18031 1/20 0.32
ABCG2 Q9UNQ0 2/20 0.31
ABCB1 P08183 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
PTGER4 P35408 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26376010 1.00 KDM4E (0.37) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL24089262 1.00 KDM4E (0.37) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL26376009 1.00 KDM4E (0.37) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL24089263 0.98 KDM4E (0.37) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL26376011 0.96 KDM4E (0.35) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL26375749 0.96 KDM4E (0.35) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL26376000 0.96 KDM4E (0.36) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL16689489 0.96 KDM4E (0.36) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL26375738 0.94 RAC2 (0.35) KDM4EATML3MBTL1RAC2RAC3
SCHEMBL26376001 0.94 RAC2 (0.35) KDM4EATML3MBTL1RAC2RAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244857-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244857-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244967-A1 Organic Light Emitting Diode and Organic Light Emitting Device Including the Same LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244967-A1 Organic Light Emitting Diode and Organic Light Emitting Device Including the Same LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20230320193-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-05 US disclosed
US-20230320193-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320193-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING LIGHT-EMITTING DEVICE CYP1A1, CRY1, CYP1B1 KDM4E 3342/4885ATM 3733/4885L3MBTL1 2292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.