Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385066 | 0.94 | HSD17B10 (0.48) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL4648214 | 0.89 | CYP19A1 (0.45) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL2638387 | 0.88 | HSD17B10 (0.57) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL4649339 | 0.88 | LMNA (0.47) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL4650084 | 0.88 | HSD17B10 (0.42) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL4648936 | 0.88 | CYP19A1 (0.42) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL4649266 | 0.86 | HSD17B10 (0.43) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL4648301 | 0.85 | MEN1 (0.45) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL2639592 | 0.85 | HSD17B1 (0.37) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL3381378 | 0.84 | HSD17B10 (0.49) | CYP19A1HSD17B10LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4718439-B2 | — | — | 2011-07-06 | — | — | JP | claimed |
| EP-1594886-A1 | ANTITUMORAL D-HOMOESTRA-1, 3, 5 (10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | Schering Aktiengesellschaft (DE) | 2005-11-16 | — | — | EP | claimed |
| WO-2004074309-A1 | ANTITUMORAL D-HOMOESTRA-1, 3, 5 (10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-02 | — | — | WO | claimed |
| EP-1594886-B1 | ANTITUMORAL D-HOMOESTRA-1, 3, 5 (10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | STERIX LTD (GB) | 2008-08-27 | — | — | EP | disclosed |
| EP-1594886-A1 | ANTITUMORAL D-HOMOESTRA-1, 3, 5 (10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | Schering Aktiengesellschaft (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004074309-A1 | ANTITUMORAL D-HOMOESTRA-1, 3, 5 (10)-TRIEN-3-YL 2-SUBSTITUTED SULFAMATES | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-02 | — | — | WO | disclosed |