SCHEMBL263770

SCHEMBL263770

NC(=O)c1ccccc1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.65
CES1 P23141 1/20 0.65
ALDH1A1 P00352 6/20 0.62
KDM4E B2RXH2 5/20 0.58
POLB P06746 2/20 0.58
KMT2A Q03164 2/20 0.57
ATM Q13315 1/20 0.57
HPGD P15428 4/20 0.56
MAPT P10636 1/20 0.56
TSHR P16473 1/20 0.56
HSD17B10 Q99714 1/20 0.56
LMNA P02545 1/20 0.53
METAP2 P50579 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
MTNR1A P48039 1/20 0.51
MTNR1B P49286 1/20 0.51
MEN1 O00255 1/20 0.51
CASP3 P42574 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29843413 1.00 CES2 (0.65) CES2CES1ALDH1A1KDM4EPOLB
SCHEMBL4873515 0.98 CES2 (0.62) CES2CES1ALDH1A1KDM4EPOLB
Hydrochloric Acid SCHEMBL404721 0.98 CES2 (0.62) CES2CES1ALDH1A1KDM4EPOLB
Hydrochloric Acid SCHEMBL4373213 0.98 CES2 (0.62) CES2CES1ALDH1A1KDM4EPOLB
Hydrochloric Acid SCHEMBL4100055 0.95 CES2 (0.60) CES2CES1ALDH1A1KDM4EPOLB
SCHEMBL3946947 0.93 CES2 (0.58) CES2CES1ALDH1A1KDM4EPOLB
SCHEMBL28865485 0.91 CES2 (0.56) CES2CES1ALDH1A1KDM4EPOLB
Acetic Acid SCHEMBL29291113 0.91 ALDH1A1 (0.59) CES2CES1ALDH1A1KDM4EPOLB
Benzamide SCHEMBL9171626 0.89 POLB (0.64) CES2CES1ALDH1A1KDM4EPOLB
Trifluoroacetic Acid SCHEMBL31069765 0.86 ALDH1A1 (0.53) CES2CES1ALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2012 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260097139-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GnRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-04-09 US claimed
EP-4103559-B1 HETEROCYCLIC PAD4 INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2026-03-04 EP claimed
EP-4634174-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-10-22 EP claimed
CN-119875232-A Flame-retardant cable and preparation method thereof 佰汇电缆有限公司 2025-04-25 CN claimed
CN-118930467-A Electrochemical synthesis method of sulfoximine fluorine and sulfodiimine fluorine compound 福州大学 2024-11-12 CN claimed
CN-118530135-A Synthesis process for synthesizing salicylamide by continuous method 镇江高鹏药业有限公司 2024-08-23 CN claimed
CN-118330104-A Pretreatment purifying tube special for quantitative analysis of tobacco pesticide residues and high-throughput detection method of tobacco pesticide residues 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) 2024-07-12 CN claimed
WO-2024129600-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-06-20 WO claimed
CN-118063402-A Synthesis process of saccharin 上海交通大学 2024-05-24 CN claimed
CN-117603095-A Chlorbenzuron hapten, antigen, antibody, detection device and preparation and application thereof 中国烟草云南进出口有限公司 2024-02-27 CN claimed
EP-0435844-A1 Substituted pyridine compounds MONSANTO COMPANY (US) 1991-07-03 EP claimed
EP-0435843-A1 Substituted pyridine compounds MONSANTO COMPANY (US) 1991-07-03 EP claimed
EP-0331052-A2 Process for the preparation of imidized acrylic polymers ELF ATOCHEM ITALIA S.r.l. (IT) 1989-09-06 EP claimed
EP-0315151-A2 Process for the preparation of imidized acrylic polymers ELF ATOCHEM ITALIA S.r.l. (IT) 1989-05-10 EP claimed
EP-0243959-A1 Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same Dainippon Pharmaceutical Co., Ltd. (JP) 1987-11-04 EP claimed
EP-0000852-B1 TREATMENT OF HERBICID CONTAINING CULTURES WITH DERIVATIVES OF DICHLOROACETAMIDE OR OF THRICHLOROACETAMIDE, NOVEL DERIVATIVES OF DICHLOROACETAMIDE OR TRICHLOROACETAMIDE AND PROCESS FOR THEIR PREPARATION P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1982-08-25 EP claimed
US-4167506-A Diazaphenalene derivatives and resin containing color compositions TEIJIN LIMITED (JP) 1979-09-11 US claimed
US-4022830-A Process for preparing polychlorobenzamide derivatives TEXACO DEVELOPMENT CORPORATION (US) 1977-05-10 US claimed
US-3943152-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed