SCHEMBL263776

SCHEMBL263776

CCCCCCCCCCCCCCCCOc1cc[c]cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.60
LTA4H P09960 4/20 0.53
TP53 P04637 2/20 0.53
TSHR P16473 2/20 0.53
PLA2G4B P0C869 3/20 0.51
RARB P10826 3/20 0.49
NPC1 O15118 1/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
RAB9A P51151 1/20 0.49
HSD17B10 Q99714 1/20 0.49
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PLA2G4A P47712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659360 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL338316 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL1609987 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL1611001 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL309133 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL987954 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL77477 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL9121701 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL988767 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL1610778 1.00 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080194859-A1 Polyurea Compositions and Compounds for the Preparation Thereof Sawyer, Kenneth I. (US) 2008-08-14 US claimed
US-7312337-B2 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY (US) 2007-12-25 US claimed
US-7268235-B2 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY (US) 2007-09-11 US claimed
EP-1751206-A2 POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF Sawyer, Kenneth I. (US) 2007-02-14 EP claimed
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes EASTMAN KODAK COMPANY 2006-04-06 US claimed
US-20060069262-A1 Oxadiazoles and their manufacture EASTMAN KODAK COMPANY 2006-03-30 US claimed
WO-2005113487-A2 POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF SAWYER KENNETH I (US) 2005-12-01 WO claimed
EP-1173411-B1 POLYALDIMINES OF OLIGOMERIC AMINOBENZOIC ACID DERIVATIVES, AND THEIR USE FOR PREPARATION OF MOISTURE-CURABLE, STORAGE-STABLE, ONE-PART POLYREAS SAWYER KENNETH I (US) 2004-04-07 EP claimed
US-6552155-B1 Blocked poly(1,4-butanediol)bis(4-aminobenzoate); formulations with polyisocyanates; rapid curing when exposed to water or air humidity; anticorrosive coating, antifouling paint, caulking, sealing, waterproofing Sawyer, Kenneth I. 2003-04-22 US claimed
US-6337176-B1 COLOR REPRODUCTION AND SHARPNESS; RAPID PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 2002-01-08 US claimed
US-6239220-B1 Recovery of triarylmethyl halide protecting groups cleaved during oligonucleotide synthesis ISIS PHARMACEUTICALS, INC. 2001-05-29 US claimed
US-6124484-A Recovery of triarylmethyl halide protecting groups cleaved during oligonucleotide synthesis ISIS PHARMACEUTICALS, INC. (US) 2000-09-26 US claimed
WO-2000004062-A1 RECOVERY OF TRIARYLMETHYL HALIDE PROTECTING GROUPS CLEAVED DURING OLIGONUCLEOTIDE SYNTHESIS ISIS PHARMACEUTICALS, INC. (US) 2000-01-27 WO claimed
WO-1999029640-A2 COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR EISAI CO., LTD. (JP) 1999-06-17 WO claimed
US-5359080-A Acetylacetamide couplers; high sensitivity, color density, spectral absorption FUJI PHOTO FILM CO., LTD. (JP) 1994-10-25 US claimed
US-5294524-A Acylacetamide yellow dye-forming couplers and aromatic amine developers FUJI PHOTO FILM CO., LTD. (JP) 1994-03-15 US claimed
US-4950764-A HERBICIDES, BACTERICIDES, ANALGESICS, ANTIINFLAMMATORY AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US claimed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
US-4477554-A SILVER HALIDE EMULSION CONTAINING QUINOID DYE-RELEASING COMPOUND AGFA-GEVAERT, N.V. (BE) 1984-10-16 US disclosed
EP-0030747-A1 2-Equivalent yellow-forming colour couplers, their use in the production of photographic colour images, and photographic elements containing such couplers AGFA-GEVAERT N.V. (BE) 1981-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194859-A1 Polyurea Compositions and Compounds for the Preparation Thereof PUF60, PCNA, PARG NR5A1 4801/4885LTA4H 4166/4885TP53 714/4885
US-20060069262-A1 Oxadiazoles and their manufacture OXA1L, CYP1B1, OXER1 NR5A1 1283/4885LTA4H 2670/4885TP53 3782/4885
US-20060074245-A1 Method for preparation of N-pyrazolylamidoximes KCNH1, KCNJ2, KCNH2 NR5A1 1937/4885LTA4H 2138/4885TP53 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.