Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | FAAH | O00519 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378216 | 0.85 | POLB (0.52) | CNR2POLBFAAHMEN1RAB9A | |
| SCHEMBL3378212 | 0.83 | POLB (0.50) | CNR2POLBFAAHMEN1RAB9A | |
| SCHEMBL28355432 | 0.81 | FAAH (0.78) | CNR2POLBFAAHMEN1KMT2A | |
| SCHEMBL2917775 | 0.81 | CNR2 (1.00) | CNR2POLBFAAHMEN1KMT2A | |
| SCHEMBL19736415 | 0.80 | CNR2 (0.76) | CNR2POLBFAAHMEN1RAB9A | |
| SCHEMBL7122051 | 0.80 | POLB (1.00) | CNR2POLBFAAHMEN1RAB9A | |
| SCHEMBL11450782 | 0.80 | CNR2 (0.73) | CNR2POLBFAAHRAB9AKMT2A | |
| SCHEMBL1421026 | 0.79 | FAAH (1.00) | CNR2POLBFAAHMEN1KMT2A | |
| SCHEMBL1883176 | 0.79 | GRM5 (0.48) | CNR2POLBFAAHMEN1RAB9A | |
| SCHEMBL22308141 | 0.77 | FAAH (0.82) | CNR2POLBFAAHPKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011529057-A | — | — | 2011-12-01 | — | — | JP | claimed |
| WO-2010011570-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | WO | claimed |