Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378752 | 0.81 | PBK (0.41) | EPHX2EPHX1 | |
| SCHEMBL3378749 | 0.79 | HSD11B1 (0.40) | EPHX2EPHX1KMT2AALDH1A1 | |
| SCHEMBL18884208 | 0.73 | EPHX2 (0.73) | EPHX2EPHX1KMT2ASMN1; SMN2FAAH | |
| SCHEMBL3069160 | 0.73 | EPHX2 (1.00) | EPHX2EPHX1JAK2ALDH1A1LMNA | |
| SCHEMBL14503288 | 0.72 | EPHX2 (0.57) | EPHX2EPHX1KMT2ASMN1; SMN2 | |
| SCHEMBL2638872 | 0.72 | EPHX2 (0.57) | EPHX2EPHX1KMT2AALDH1A1 | |
| SCHEMBL1694443 | 0.72 | EPHX2 (0.70) | EPHX2EPHX1KMT2ASMN1; SMN2FAAH | |
| SCHEMBL30500314 | 0.72 | EPHX2 (0.70) | EPHX2EPHX1KMT2ASMN1; SMN2FAAH | |
| SCHEMBL2638571 | 0.71 | EPHX2 (0.59) | EPHX2EPHX1KMT2AALDH1A1 | |
| SCHEMBL4862054 | 0.71 | HDAC3 (0.64) | EPHX2EPHX1KMT2ASMN1; SMN2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011529057-A | — | — | 2011-12-01 | — | — | JP | claimed |
| WO-2010011570-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | WO | claimed |