Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 2/20 | 0.67 |
| ▸ | CNR2 | P34972 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1579002 | 0.92 | FAAH (0.60) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL14503290 | 0.89 | FAAH (0.82) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL2638502 | 0.87 | FAAH (0.55) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL1578168 | 0.86 | GRM5 (0.55) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL12672470 | 0.84 | GRM5 (0.53) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL2638487 | 0.84 | GRM5 (0.53) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL31490945 | 0.84 | FAAH (1.00) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL3381777 | 0.84 | FAAH (1.00) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL16244486 | 0.83 | GRM5 (0.62) | FAAHKMT2AATMCNR2MEN1 | |
| SCHEMBL1578352 | 0.83 | GRM5 (0.55) | FAAHKMT2AATMCNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011529057-A | — | — | 2011-12-01 | — | — | JP | claimed |
| WO-2010011570-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | WO | claimed |