SCHEMBL31490945

SCHEMBL31490945

O=C(NC12CC3CC(CC(C3)C1)C2)c1cccc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 1.00
CNR2 P34972 5/20 0.68
KMT2A Q03164 2/20 0.67
MEN1 O00255 1/20 0.67
ATM Q13315 2/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
KDM4E B2RXH2 2/20 0.62
HSD17B10 Q99714 2/20 0.62
EPHX2 P34913 1/20 0.62
TSHR P16473 2/20 0.60
ALDH1A1 P00352 1/20 0.60
MAPT P10636 1/20 0.60
HPGD P15428 1/20 0.60
ALOX12 P18054 1/20 0.60
HTT P42858 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
POLB P06746 1/20 0.57
PKM P14618 1/20 0.57
EPHX1 P07099 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3381777 1.00 FAAH (1.00) FAAHCNR2KMT2AMEN1ATM
SCHEMBL14503290 0.91 FAAH (0.82) FAAHCNR2KMT2AMEN1ATM
SCHEMBL3376422 0.85 FAAH (0.74) FAAHCNR2KMT2AMEN1ATM
SCHEMBL7093602 0.84 FAAH (0.72) FAAHCNR2KMT2AMEN1ATM
SCHEMBL2638136 0.84 FAAH (0.72) FAAHCNR2KMT2AMEN1ATM
SCHEMBL19354776 0.84 FAAH (0.72) FAAHCNR2KMT2AMEN1ATM
SCHEMBL3376419 0.83 FAAH (0.70) FAAHCNR2KMT2AMEN1ATM
SCHEMBL1421026 0.82 FAAH (1.00) FAAHCNR2KMT2AMEN1ATM
SCHEMBL2917775 0.81 CNR2 (1.00) FAAHCNR2KMT2AMEN1ATM
SCHEMBL2639379 0.80 FAAH (0.67) FAAHCNR2KMT2AMEN1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119822990-A Adamantane isopropanolamine structure compound and preparation method and application thereof 贵州大学 2025-04-15 CN disclosed