Isopropylbenzene

Isopropylbenzene

SCHEMBL2638430

C1CCCCC1.CC(C)c1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 5/20 0.48
CYP1A2 P05177 4/20 0.46
CYP3A4 P08684 4/20 0.46
CYP2C9 P11712 4/20 0.46
KCNA5 P22460 4/20 0.46
CYP2C19 P33261 4/20 0.46
KCNH2 Q12809 4/20 0.46
KCNE1 P15382 1/20 0.46
GAA P10253 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TAAR1 Q96RJ0 2/20 0.44
ADRA2A P08913 1/20 0.42
ADRA2C P18825 1/20 0.42
LMNA P02545 1/20 0.42
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MC4R P32245 1/20 0.41
DPP4 P27487 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylbenzene SCHEMBL8431863 0.91 TAAR1 (0.50) CYP2D6TAAR1ADRA2AADRA2CLMNA
Isopropylbenzene SCHEMBL6568 0.91
Isopropylbenzene SCHEMBL3672803 0.91 TAAR1 (0.50) CYP2D6TAAR1ADRA2AADRA2CLMNA
Isopropylbenzene SCHEMBL11254813 0.91
Isopropylbenzene SCHEMBL87809 0.91 TAAR1 (0.50) CYP2D6TAAR1ADRA2AADRA2CLMNA
Isopropylbenzene SCHEMBL23421101 0.88 ADRA2C (0.52) CYP2D6CYP3A4CYP2C9CYP2C19TAAR1
Isopropylbenzene SCHEMBL3198660 0.88 TAAR1 (0.48) CYP2D6TAAR1ADRA2AADRA2CLMNA
Isopropylbenzene SCHEMBL18614726 0.88 ADRA2C (0.52) CYP2D6CYP3A4CYP2C9CYP2C19TAAR1
Isopropylbenzene SCHEMBL9352133 0.88 TAAR1 (0.48) CYP2D6TAAR1ADRA2AADRA2CLMNA
Isopropylbenzene SCHEMBL9725943 0.88 TAAR1 (0.48) CYP2D6TAAR1ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4792550-B2 2011-10-12 JP claimed
EP-1608634-A4 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE PHARMION CORP (US) 2006-03-15 EP claimed
EP-1608634-A2 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE Pharmion Corporation (US) 2005-12-28 EP claimed
WO-2004082822-A2 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE PHARMION CORPORATION (US) 2004-09-30 WO claimed
CN-116212879-A Alpha-methylstyrene hydrogenation catalyst, preparation method and application thereof 上海优铖工逸技术有限公司 2023-06-06 CN disclosed
CN-116023206-A Device and method for preparing isopropylbenzene by hydrogenolysis of alpha, alpha-dimethylbenzyl alcohol 万华化学集团股份有限公司 2023-04-28 CN disclosed
CN-113058628-A Pd-C catalyst for preparing cumene through hydrogenolysis and preparation method thereof 万华化学集团股份有限公司 2021-07-02 CN disclosed
CN-107552031-B Preparation method and application of titanium-containing silicon oxide material 东联化学股份有限公司 2020-12-11 CN disclosed
US-20200298218-A1 METHOD OF USING BIOPOLYMER TO SYNTHESIZE TITANIUM-CONTAINING SILICON OXIDE MATERIAL AND APPLICATIONS THEREOF ORIENTAL UNION CHEMICAL CORP. (TW) 2020-09-24 US disclosed
US-10780431-B1 Method of using biopolymer to synthesize titanium-containing silicon oxide material and applications thereof ORIENTAL UNION CHEMICAL CORP. (TW) 2020-09-22 US disclosed
US-10744493-B1 Method of using biopolymer to synthesize titanium-containing silicon oxide material and applications thereof ORIENTAL UNION CHEMICAL CORP. (TW) 2020-08-18 US disclosed