SCHEMBL2638461

SCHEMBL2638461

CC(=Cc1cccc(C)c1C(=O)O)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC9A3 P48764 3/20 0.37
SLC9A1 P19634 2/20 0.37
MYC P01106 1/20 0.37
SLC9A2 Q9UBY0 1/20 0.36
CYP19A1 P11511 1/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 2/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
MCL1 Q07820 1/20 0.34
GPR52 Q9Y2T5 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
FABP3 P05413 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4744668 0.81 ALDH1A1 (0.47) L3MBTL1TDP1SLC9A3SLC9A1MYC
SCHEMBL1681467 0.80 ALDH1A1 (0.43) L3MBTL1SLC9A3SLC9A1SLC9A2KDM4E
SCHEMBL7449933 0.77 AKR1C3 (0.43) L3MBTL1TDP1SLC9A3SLC9A1SLC9A2
SCHEMBL2320182 0.75 ALDH1A1 (0.54) L3MBTL1TDP1MYCCYP19A1KDM4E
SCHEMBL9068444 0.75 ALDH1A1 (0.45) TDP1MYCKDM4EALDH1A1HPGD
SCHEMBL937372 0.75 ALDH1A1 (0.45) TDP1MYCKDM4EALDH1A1HPGD
SCHEMBL935931 0.74 TDP1 (0.47) L3MBTL1TDP1MYCCYP19A1KDM4E
SCHEMBL16668526 0.74 TDP1 (0.47) L3MBTL1TDP1MYCCYP19A1KDM4E
SCHEMBL355272 0.72 TDP1 (0.61) L3MBTL1TDP1MYCKDM4EALDH1A1
SCHEMBL3865338 0.70 MAPT (0.52) L3MBTL1TDP1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4748806-B2 2011-08-17 JP claimed
US-7211316-B2 Optical multilayer NITTO DENKO CORPORATION (JP) 2007-05-01 US claimed
WO-2005045820-A1 OPTICAL MULTILAYER EASTMAN KODAK COMPANY (US) 2005-05-19 WO claimed
US-20050089676-A1 Optical multilayer EASTMAN KODAK COMPANY 2005-04-28 US claimed