Tetrahydrothiophene

Tetrahydrothiophene

SCHEMBL2638503

C1CCSC1.CC(C)(C)COCC(C)(C)C

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL2638205 0.87 ALDH1A1 (0.32)
Cyclohexane SCHEMBL3216822 0.80 CYP2C19 (0.36)
SCHEMBL18191 0.76 CYP2C19 (0.42)
SCHEMBL28557000 0.73 CYP2C19 (0.40)
Hydrochloric Acid SCHEMBL8858515 0.73 CYP2C19 (0.40)
Ammonia Solution, Strong SCHEMBL27688316 0.73 CYP2C19 (0.40)
Fluoride SCHEMBL15313130 0.70 CYP2C19 (0.38)
Ethylene SCHEMBL4765785 0.70 CYP2C19 (0.38)
Fluoride SCHEMBL732880 0.70 CYP2C19 (0.38)
Methyl Alcohol SCHEMBL4271767 0.70 CYP2C19 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4792550-B2 2011-10-12 JP claimed
EP-1608634-A4 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE PHARMION CORP (US) 2006-03-15 EP claimed
EP-1608634-A2 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE Pharmion Corporation (US) 2005-12-28 EP claimed
WO-2004082822-A2 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE PHARMION CORPORATION (US) 2004-09-30 WO claimed