Tetrahydrofuran

Tetrahydrofuran

SCHEMBL2638205

C1CCOC1.C1CCSC1.CC(C)(C)COCC(C)(C)C

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrothiophene SCHEMBL2638503 0.87
Tetrahydrofuran SCHEMBL1682253 0.75 ALDH1A1 (0.57) ALDH1A1
Tetrahydrofuran SCHEMBL7235639 0.75 ALDH1A1 (0.57) ALDH1A1
Tetrahydrothiophene SCHEMBL15200771 0.72 ALDH1A1 (0.53) ALDH1A1
SCHEMBL15550392 0.72 ALDH1A1 (0.53) ALDH1A1
Tetrahydrothiophene SCHEMBL11806226 0.72 ALDH1A1 (0.53) ALDH1A1
SCHEMBL2587435 0.72 ALDH1A1 (0.53) ALDH1A1
SCHEMBL14116483 0.72
SCHEMBL10505667 0.72 ALDH1A1 (0.53) ALDH1A1
Tetrahydrothiophene SCHEMBL5987312 0.72 ALDH1A1 (0.53) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4792550-B2 2011-10-12 JP claimed
EP-1608634-A4 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE PHARMION CORP (US) 2006-03-15 EP claimed
EP-1608634-A2 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE Pharmion Corporation (US) 2005-12-28 EP claimed
WO-2004082822-A2 METHODS FOR ISOLATING CRYSTALLINE FORM I OF 5-AZACYTIDINE PHARMION CORPORATION (US) 2004-09-30 WO claimed