SCHEMBL2638825

SCHEMBL2638825

CCCCCCCCCCCCCCCCC(O)CN(CCO)C(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.51
FFAR1 O14842 2/20 0.51
GPR84 Q9NQS5 5/20 0.45
FAAH O00519 2/20 0.43
PSMD14 O00487 2/20 0.43
PLA2G1B P04054 2/20 0.43
MMP2 P08253 2/20 0.43
ATG4B Q9Y4P1 2/20 0.43
HSP90AA1 P07900 1/20 0.43
RAD52 P43351 1/20 0.43
NFKB1 P19838 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080766 1.00 FFAR4 (0.51) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL8081194 1.00 FFAR4 (0.51) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL8053818 1.00 FFAR4 (0.51) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL2637960 1.00 FFAR4 (0.51) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL2638062 1.00 FFAR4 (0.51) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL18038938 1.00 FFAR4 (0.51) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL25139921 1.00 FFAR4 (0.51) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL9511963 1.00 FFAR4 (0.51) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL7584644 0.95 FFAR1 (0.46) FFAR4FFAR1GPR84FAAHPSMD14
SCHEMBL2639555 0.95 FFAR1 (0.46) FFAR4FFAR1GPR84FAAHPSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1534213-B1 WATER-BASED DELIVERY SYSTEMS SKOELD THOMAS (SE) 2013-04-24 EP claimed
JP-4806519-B2 2011-11-02 JP claimed
US-20090226491-A1 Water-based delivery systems SKOLD, THOMAS (SE) 2009-09-10 US claimed
US-20090081139-A1 Water-based delivery systems GALDERMA LABORATORIES, INC. 2009-03-26 US claimed
WO-2006039667-A2 WATER-BASED DELIVERY SYSTEMS COLLAGENEX PHARMACEUTICALS, INC. (US) 2006-04-13 WO claimed
EP-1534213-A4 WATER-BASED DELIVERY SYSTEMS COLLAGENEX PHARM INC (US) 2005-10-26 EP claimed
US-20050129722-A1 For an active substance, characterized by enhancing skin barrier restoration in the stratum corneum comprising a fatty acid, cholesterol, a ceramide and at least one skin lipid precursor; topical drug delivery COLLAGENEX PHARMACEUTICALS, INC. 2005-06-16 US claimed
EP-1534213-A2 WATER-BASED DELIVERY SYSTEMS Collagenex Pharmaceuticals, Inc. (US) 2005-06-01 EP claimed
US-20040009213-A1 Water-based delivery systems COLLAGENEX PHARMACEUTICALS, INC. 2004-01-15 US claimed
WO-2003077861-A2 WATER-BASED DELIVERY SYSTEMS COLLAGENEX PHARMACEUTICALS, INC. (US) 2003-09-25 WO claimed
EP-1534213-B1 WATER-BASED DELIVERY SYSTEMS SKOELD THOMAS (SE) 2013-04-24 EP disclosed
US-20090226491-A1 Water-based delivery systems SKOLD, THOMAS (SE) 2009-09-10 US disclosed
US-20090081139-A1 Water-based delivery systems GALDERMA LABORATORIES, INC. 2009-03-26 US disclosed
WO-2006039667-A2 WATER-BASED DELIVERY SYSTEMS COLLAGENEX PHARMACEUTICALS, INC. (US) 2006-04-13 WO disclosed
EP-1534213-A4 WATER-BASED DELIVERY SYSTEMS COLLAGENEX PHARM INC (US) 2005-10-26 EP disclosed
EP-1534213-A2 WATER-BASED DELIVERY SYSTEMS Collagenex Pharmaceuticals, Inc. (US) 2005-06-01 EP disclosed
US-20040009213-A1 Water-based delivery systems COLLAGENEX PHARMACEUTICALS, INC. 2004-01-15 US disclosed
WO-2003077861-A2 WATER-BASED DELIVERY SYSTEMS COLLAGENEX PHARMACEUTICALS, INC. (US) 2003-09-25 WO disclosed
EP-0711558-A1 Compositions for topical application to skin, hair and nails UNILEVER PLC (GB) 1996-05-15 EP disclosed
US-5476661-A Mixture of 25-hydroxycholecalciferol, a ceramide lipid, and a carrier; keratinocyte prodifferentiation, cosmetics ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) 1995-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050129722-A1 For an active substance, characterized by enhancing skin barrier restoration in the stratum corneum comprising a fatty acid, cholesterol, a ceramide and at least one skin lipid precursor; topical drug delivery CERT1, CERS2, SGMS1 FFAR4 280/4885FFAR1 205/4885GPR84 568/4885
US-20090226491-A1 Water-based delivery systems CERS2, SGMS2, SGMS1 FFAR4 451/4885FFAR1 288/4885GPR84 682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.