Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25648965 | 0.80 | PDE2A (0.34) | PDE2A | |
| SCHEMBL1662616 | 0.77 | PDE2A (0.33) | PDE2A | |
| SCHEMBL24977818 | 0.77 | — | — | |
| SCHEMBL26389378 | 0.77 | MAT2A (0.30) | — | |
| SCHEMBL25647871 | 0.76 | PDE2A (0.33) | PDE2A | |
| SCHEMBL24977207 | 0.75 | — | — | |
| SCHEMBL26388352 | 0.74 | CSF1R (0.33) | — | |
| SCHEMBL26388629 | 0.74 | — | — | |
| SCHEMBL25109188 | 0.73 | SMN1; SMN2 (0.39) | PDE2A | |
| SCHEMBL23880200 | 0.73 | HTT (0.33) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |