Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26389004 | 0.86 | — | — | |
| SCHEMBL1359371 | 0.80 | LRRK2 (0.36) | LRRK2FFAR1LMNAPOLB | |
| SCHEMBL17076655 | 0.80 | LRRK2 (0.36) | LRRK2FFAR1LMNAPOLB | |
| SCHEMBL24013536 | 0.79 | LRRK2 (0.33) | LRRK2 | |
| SCHEMBL1358932 | 0.77 | LRRK2 (0.38) | LRRK2FFAR1 | |
| SCHEMBL26388988 | 0.77 | FFAR1 (0.34) | LRRK2FFAR1 | |
| SCHEMBL21408586 | 0.76 | LMNA (0.39) | LRRK2LMNAPOLB | |
| SCHEMBL26388984 | 0.76 | FFAR1 (0.36) | LRRK2FFAR1 | |
| SCHEMBL21819821 | 0.75 | ACHE (0.31) | — | |
| SCHEMBL20606770 | 0.75 | ACHE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |