Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.47 |
| ▸ | CDK2 | P24941 | 5/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 4/20 | 0.47 |
| ▸ | CLK2 | P49760 | 4/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.47 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.47 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26396309 | 0.85 | LRRK2 (0.45) | GSK3BDYRK1ACDK2DAPK3CLK2 | |
| SCHEMBL26394149 | 0.84 | GSK3B (0.46) | GSK3BCDK2GSK3APIM1 | |
| SCHEMBL26396381 | 0.84 | GSK3B (0.40) | GSK3BDYRK1ACDK2DAPK3CLK2 | |
| SCHEMBL26397024 | 0.84 | LRRK2 (0.41) | GSK3BDYRK1ACDK2DAPK3CLK2 | |
| Hydrochloric Acid SCHEMBL26132206 | 0.83 | GSK3B (0.45) | GSK3BCDK2GSK3APIM1 | |
| Hydrochloric Acid SCHEMBL26132356 | 0.83 | GSK3B (0.40) | GSK3BDYRK1ACDK2DAPK3CLK2 | |
| SCHEMBL26396394 | 0.82 | ULK1 (0.41) | GSK3BDYRK1ACDK2DAPK3CLK2 | |
| SCHEMBL26395004 | 0.82 | GSK3B (0.47) | GSK3BDYRK1ACDK2GSK3APIM1 | |
| Hydrochloric Acid SCHEMBL26132402 | 0.82 | ULK1 (0.43) | GSK3BDYRK1ACDK2DAPK3CLK2 | |
| SCHEMBL26396503 | 0.81 | GSK3B (0.41) | GSK3BDYRK1ACDK2DAPK3CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |