Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 3/20 | 0.40 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13687178 | 0.85 | MAP2K4 (0.42) | MAP2K4FABP4BRAFMAPTEP300 | |
| SCHEMBL3529771 | 0.85 | FABP4 (0.53) | MAP2K4FABP4BRAFNEU3MAPT | |
| SCHEMBL9931060 | 0.84 | BRAF (0.49) | MAP2K4BRAFMAP2K1CYP3A4CYP2C9 | |
| SCHEMBL26401647 | 0.83 | CYP2C9 (0.42) | FABP4BRAFMAP2K1CA2CYP3A4 | |
| SCHEMBL3019904 | 0.83 | BRAF (0.51) | FABP4BRAFMAP2K1CA2 | |
| SCHEMBL3526302 | 0.83 | KDM4E (0.47) | MAP2K4FABP4BRAFMAPTCYP2C9 | |
| SCHEMBL13687251 | 0.83 | BRAF (0.43) | MAP2K4FABP4BRAFMAPT | |
| SCHEMBL13747696 | 0.81 | BRAF (0.42) | MAP2K4FABP4BRAFMAP2K1CYP3A4 | |
| SCHEMBL13719484 | 0.81 | FABP4 (0.42) | MAP2K4FABP4BRAFMAPT | |
| SCHEMBL13687086 | 0.81 | MAP2K4 (0.40) | MAP2K4FABP4CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |