Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PLAT | P00750 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929414 | 0.80 | PLG (0.56) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL3424858 | 0.80 | PLG (0.56) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL20501700 | 0.78 | PLG (0.54) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL20501699 | 0.78 | PLG (0.54) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL542144 | 0.78 | — | — | |
| SCHEMBL7355454 | 0.77 | — | — | |
| SCHEMBL2639277 | 0.76 | TP53 (0.40) | ALDH1A1NPC1RAB9A | |
| SCHEMBL11664391 | 0.74 | LMNA (0.65) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL125689 | 0.74 | LMNA (0.65) | PLGPLATLMNAANPEPENPEP | |
| Cyclopropane Carboxylic Acid SCHEMBL4643 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4837831-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| US-20070265440-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY RESPONSE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2007-11-15 | — | — | US | claimed |
| CN-1191266-C | Compositions for treating inflammatory response | UNIV VIRGINIA (US) | 2005-03-02 | — | — | CN | claimed |
| EP-1194440-B1 | INDUCTION OF PHARMACOLOGICAL STRESS WITH ADENOSINE RECEPTOR AGONISTS | UNIV VIRGINIA (US) | 2005-02-16 | — | — | EP | claimed |
| EP-1150991-B1 | COMPOSITIONS FOR TREATING INFLAMMATORY RESPONSE | UNIV VIRGINIA (US) | 2004-04-07 | — | — | EP | claimed |
| US-20030162742-A1 | Methods and compositions for treating inflammatory response | UNIVERSITY OF VIRGINIA PATENT FOUNDATION, UNIVERSITY OF VIRGINIA. | 2003-08-28 | — | — | US | claimed |
| US-6531457-B2 | A2A adenosine receptor antagonists such as methyl-4-(3-(9-(5-(N-ethylcarbamoyl)-3,4-dihydrooxolan-2-yl)-6-aminopurin-2 -yl))prop-2-ynyl)cyclohexane-carboxylate | UNIVERSITY OF VIRGINIA | 2003-03-11 | — | — | US | claimed |
| CN-1357002-A | Compositions for treating inflammatory responses | UNIV VIRGINIA (US) | 2002-07-03 | — | — | CN | claimed |
| EP-1194440-A2 | INDUCTION OF PHARMACOLOGICAL STRESS WITH ADENOSINE RECEPTOR AGONISTS | THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2002-04-10 | — | — | EP | claimed |
| US-6322771-B1 | PARENTERALLY ADMINISTERING TO A MAMMAL A PURINE DERIVATIVE TO DIAGNOSE CORONARY ARTERY STENOSIS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2001-11-27 | — | — | US | claimed |
| EP-1150991-A2 | COMPOSITIONS FOR TREATING INFLAMMATORY RESPONSE | THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2001-11-07 | — | — | EP | claimed |
| US-20010027185-A1 | Methods and compositions for treating inflammatory response | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2001-10-04 | — | — | US | claimed |
| US-6232297-B1 | ADMINISTERING 4-AMINOPYRROLO(3,2-D)PYRIMIDINE DERIVATIVE AS ADENOSINE RECEPTOR ANTAGONIST | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2001-05-15 | — | — | US | claimed |
| WO-2000078774-A2 | INDUCTION OF PHARMACOLOGICAL STRESS WITH ADENOSINE RECEPTOR AGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000044763-A2 | COMPOSITIONS FOR TREATING INFLAMMATORY RESPONSE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2000-08-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265440-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY RESPONSE | ADORA2A, ADORA2B, LTB4R2 | PLG 537/4885PLAT 807/4885LMNA 3335/4885 |
| US-20030162742-A1 | Methods and compositions for treating inflammatory response | ADORA2A, P2RY2, LTB4R2 | PLG 800/4885PLAT 772/4885LMNA 3143/4885 |
| US-20010027185-A1 | Methods and compositions for treating inflammatory response | LTB4R2, ADORA2A, PTGES2 | PLG 341/4885PLAT 495/4885LMNA 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.