Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640272 | 1.00 | TERT (0.31) | TERTPABPC1APOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL1692886 | 0.95 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL1692646 | 0.95 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL4595854 | 0.88 | — | — | |
| SCHEMBL4969704 | 0.83 | — | — | |
| SCHEMBL4578455 | 0.80 | MEN1 (0.33) | MEN1TSHRKMT2A | |
| SCHEMBL4595922 | 0.80 | MEN1 (0.31) | MEN1TSHRKMT2A | |
| SCHEMBL1516369 | 0.78 | MEN1 (0.32) | MEN1TSHRKMT2A | |
| SCHEMBL7162202 | 0.75 | MEN1 (0.38) | MEN1TSHRKMT2A | |
| SCHEMBL1693060 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149841-A1 | SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-α MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-12-01 | — | — | WO | disclosed |