SCHEMBL264070

SCHEMBL264070

Cc1cc(Br)ccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29391325 1.00
Fluoride SCHEMBL27279145 0.97 ALDH1A1 (0.42)
Fluoride SCHEMBL27598987 0.97 ALDH1A1 (0.42)
Magnesium SCHEMBL31567264 0.97 ALDH1A1 (0.42)
SCHEMBL168931 0.79
Chlorocresol SCHEMBL875121 0.78 ALOX15 (0.52)
SCHEMBL3747323 0.77 CYP3A4 (0.50)
SCHEMBL40336 0.75
SCHEMBL125688 0.75
SCHEMBL29419590 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652170-A New synthesis method of 5-bromo-2-chlorobenzoic acid 宁夏法安德药业有限公司 2024-09-17 CN claimed
CN-107652276-A A kind of preparation method net SGLT2 inhibitor Yi Palie 江苏工程职业技术学院 2018-02-02 CN claimed
CN-104478670-B The preparation method of the bromo-2-of 5-chloro-4 '-ethoxy diphenyl methane 中国药科大学 2016-08-17 CN claimed
JP-54151945-A None JP disclosed
CN-116829545-B Substituted pyrazolylpiperidine carboxylic acids 拜耳公司 2026-05-15 CN disclosed
US-20260124309-A1 STAT6 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-05-07 US disclosed
US-20250388606-A1 AZAQUINAZOLINE PAN-KRAS INHIBITORS MIRATI THERAPEUTICS INC (US) 2025-12-25 US disclosed
WO-2025228892-A1 MONOARYL AND HETARYL SUBSTITUTED INDAZOLES AND BENZIMIDAZOLES AS STING ANTAGONISTS AND THE USE THEREOF AS MEDICAMENT BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-11-06 WO disclosed
US-20250333398-A1 MONOARYL AND HETARYL SUBSTITUTED INDAZOLES AND BENZIMIDAZOLES AS STING ANTAGONISTS AND THE USE THEREOF AS MEDICAMENT BOEHRINGER INGELHEIM INT (DE) 2025-10-30 US disclosed
US-12398154-B2 Azaquinazoline pan-KRas inhibitors Mirati Therapeutics, Inc. (US) 2025-08-26 US disclosed
CN-120208766-A Dapagliflozin intermediate bromine of (2) Process and apparatus for producing substitute 浙江江北南海药业有限公司 2025-06-27 CN disclosed
US-5380848-A 8-azabicyclo(3.2.1)octanes RESEARCH TRIANGLE INSTITUTE (US) 1995-01-10 US disclosed
EP-0644775-A4 COCAINE RECEPTOR BINDING LIGANDS. RES TRIANGLE INST (US) 1994-10-19 EP disclosed
WO-1993009814-A1 COCAINE RECEPTOR BINDING LIGANDS RESEARCH TRIANGLE INSTITUTE (US) 1993-05-27 WO disclosed
US-5138031-A LINEAR AND BRANCHED POLY-P-ARYLENE SULFIDE SUBSTANTIALLY FREE FROM DEFECT STRUCTURES HAVING PLURAL ABSORPTION MAXIMA BAYER AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
EP-0077537-B1 PROCESS FOR PREPARING 6-CHLORO-3-TOLUIDINO-4-SULPHONIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1985-10-02 EP disclosed
US-RE31412-E FLUORAN COMPOUND AS COLOR-FORMER YAMAMOTO KAGAKU GOSEI KABUSHIKI KAISHA (JP) 1983-10-11 US disclosed
EP-0077537-A2 Process for preparing 6-chloro-3-toluidino-4-sulphonic acid HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-27 EP disclosed
JP-S54151945-A PREPARATION OF 6-CHLORO-3-TOLUIDINE-4-SULFONIC ACID HODOGAYA CHEM CO LTD 1979-11-29 JP disclosed
US-3947460-A SEDATIVES-HYPNOTIC, TRANQUILIZER SANDOZ, INC. (US) 1976-03-30 US disclosed