Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17673275 | 0.77 | CYP1A2 (0.58) | KDM4ELMNAL3MBTL1KMT2ACYP1A2 | |
| SCHEMBL4272819 | 0.77 | SLC2A1 (0.56) | HTR3AKDM1ANUDT1SLC2A1KDM4E | |
| SCHEMBL29029744 | 0.75 | MYC (0.46) | KDM4EL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL3291837 | 0.75 | TDP1 (0.43) | KDM4ELMNAL3MBTL1HTTKMT2A | |
| SCHEMBL1238925 | 0.75 | CYP1A2 (0.60) | HTR3ALMNAL3MBTL1MEN1HTT | |
| SCHEMBL6462106 | 0.74 | IGF1R (0.52) | HTR3AKDM1ANUDT1KDM4EL3MBTL1 | |
| SCHEMBL16009200 | 0.74 | HTR3A (0.51) | HTR3AKDM1ANUDT1SLC2A1KDM4E | |
| SCHEMBL29632453 | 0.74 | MAOA (0.45) | KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL25110127 | 0.73 | TLR7 (0.65) | HTR3ATLR7NUDT1MEN1KMT2A | |
| SCHEMBL19148204 | 0.71 | MAOA (0.38) | KDM4EL3MBTL1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |