Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 6/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26409928 | 0.82 | CACNA1H (0.61) | CACNA1HEPHX2KMT2AEPHX1KDM4E | |
| SCHEMBL26409172 | 0.81 | CACNA1H (0.43) | CACNA1HEPHX2EPHX1KDM4EALDH1A1 | |
| SCHEMBL26409165 | 0.73 | ALDH1A1 (0.43) | CACNA1HEPHX2EPHX1KDM4EALDH1A1 | |
| SCHEMBL26409170 | 0.73 | EPHX2 (0.35) | EPHX2EPHX1ALDH1A1 | |
| SCHEMBL26409689 | 0.70 | CACNA1H (0.45) | CACNA1HKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26082692 | 0.69 | CACNA1H (0.74) | CACNA1HEPHX2KMT2AEPHX1KDM4E | |
| SCHEMBL26465836 | 0.67 | CACNA1H (0.56) | CACNA1HEPHX2EPHX1KDM4EALDH1A1 | |
| SCHEMBL2638872 | 0.66 | EPHX2 (0.57) | EPHX2KMT2AEPHX1ALDH1A1 | |
| SCHEMBL26353760 | 0.66 | EPHX2 (0.48) | EPHX2KMT2ASMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL2638571 | 0.65 | EPHX2 (0.59) | EPHX2KMT2AEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |