Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408251 | 0.90 | CACNA1H (0.43) | CACNA1HMAPTMGLLSMN1; SMN2KDM4E | |
| SCHEMBL26408044 | 0.88 | CACNA1H (0.48) | CACNA1HMEN1KMT2AMGLLSMN1; SMN2 | |
| SCHEMBL26408263 | 0.87 | CACNA1H (0.42) | CACNA1HMAPTMEN1KMT2AMGLL | |
| SCHEMBL26408695 | 0.87 | SMN1; SMN2 (0.48) | MAPTMEN1KMT2AMGLLSMN1; SMN2 | |
| SCHEMBL26409300 | 0.86 | CACNA1H (0.45) | CACNA1HMEN1KMT2AMGLLSMN1; SMN2 | |
| SCHEMBL26408685 | 0.84 | TP53 (0.44) | MAPTKMT2AMGLLALDH1A1TP53 | |
| SCHEMBL26409298 | 0.84 | MALT1 (0.41) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL26408937 | 0.83 | HRH2 (0.40) | CACNA1HMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL26408699 | 0.81 | MALT1 (0.47) | CACNA1HMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26408686 | 0.81 | MAPT (0.43) | MAPTKMT2AMGLLALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |