Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408686 | 0.96 | MAPT (0.43) | TP53MAPTMGLLMALT1ALPL | |
| SCHEMBL26408701 | 0.89 | NPSR1 (0.49) | KMT2AALDH1A1 | |
| SCHEMBL26408699 | 0.88 | MALT1 (0.47) | MALT1KMT2AALDH1A1 | |
| SCHEMBL26408693 | 0.87 | LMNA (0.41) | MAPTMGLLPOLB | |
| SCHEMBL26408044 | 0.87 | CACNA1H (0.48) | MGLLKMT2AALDH1A1 | |
| SCHEMBL26408695 | 0.86 | SMN1; SMN2 (0.48) | TP53MAPTMGLLKMT2AALDH1A1 | |
| SCHEMBL26408707 | 0.86 | MGLL (0.43) | TP53MAPTMGLLMALT1KMT2A | |
| SCHEMBL26408696 | 0.85 | SMN1; SMN2 (0.47) | TP53MAPTKMT2AALDH1A1POLB | |
| SCHEMBL26408939 | 0.84 | NPY5R (0.43) | TP53MAPTKMT2A | |
| SCHEMBL26408948 | 0.84 | SIGMAR1 (0.47) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |