SCHEMBL2641050

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2641162	0.84	HTR1A (0.43)	ALDH1A1CYP1A2CASP1CASP7HSD17B10
	SCHEMBL2641032	0.84	RXFP1 (0.42)	HTR2CMAPK1
	SCHEMBL2641018	0.83	HRH3 (0.49)	PARP1ALDH1A1HPGDTSHRHRH3
	SCHEMBL2640994	0.83	HTR2C (0.43)	HTR2CALDH1A1KDM4E
	SCHEMBL2641132	0.83	HTR2C (0.47)	HTR2CALDH1A1KDM4E
	SCHEMBL2641342	0.83	HRH3 (0.48)	HTR2CHRH3
	SCHEMBL2641243	0.82	MEN1 (0.44)	ALDH1A1CYP1A2CYP3A4CYP2C9TSHR
	SCHEMBL2640922	0.82	HTR1A (0.47)	HTR2CALDH1A1KDM4E
	SCHEMBL2641416	0.82	HTR6 (0.46)	HTR2CALDH1A1CYP1A2HPGDCASP1
	SCHEMBL2641183	0.82	KDM4E (0.42)	HTR2CALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.