Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.51 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19186103 | 0.90 | RAB9A (0.47) | NOTUMALDH1A1LMNACYP2C19MEN1 | |
| SCHEMBL26545466 | 0.87 | F2 (0.45) | NOTUMLMNATSHRMEN1KMT2A | |
| SCHEMBL26439861 | 0.83 | KMT2A (0.44) | LMNACYP2D6TSHRMEN1KMT2A | |
| SCHEMBL27772891 | 0.83 | KMT2A (0.44) | ALDH1A1LMNACYP2D6TSHRMEN1 | |
| SCHEMBL28781857 | 0.83 | KMT2A (0.44) | LMNACYP2D6TSHRMEN1KMT2A | |
| SCHEMBL20306078 | 0.83 | KMT2A (0.44) | LMNATSHRMEN1KMT2ACHRNB2 | |
| SCHEMBL25629349 | 0.81 | KMT2A (0.47) | LMNATSHRMEN1KMT2ACHRNB2 | |
| SCHEMBL27808181 | 0.80 | KMT2A (0.43) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL29111290 | 0.79 | SLC18A3 (0.57) | ALDH1A1LMNAMEN1KMT2ACHRNB2 | |
| SCHEMBL20306077 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169922-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |