Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508008 | 0.75 | APP (1.00) | APPTRPA1FAAH | |
| SCHEMBL20004068 | 0.72 | TRPA1 (0.55) | APPTRPA1FAAHARKDM1A | |
| SCHEMBL19998605 | 0.72 | TRPA1 (0.51) | APPTRPA1FAAHARCCNC | |
| SCHEMBL29304447 | 0.71 | TRPA1 (0.48) | APPTRPA1FAAHARKDM5B | |
| SCHEMBL19998599 | 0.71 | TRPA1 (0.48) | APPTRPA1FAAHARKDM5B | |
| SCHEMBL13106148 | 0.71 | HTR2A (0.53) | APPTRPA1MAOBCDC7TRPM5 | |
| SCHEMBL20004107 | 0.71 | TRPA1 (0.50) | APPTRPA1FAAHARCCNC | |
| SCHEMBL13680459 | 0.71 | APP (0.49) | APPTRPA1FAAHARKDM5B | |
| SCHEMBL15345061 | 0.70 | TRPA1 (0.47) | APPTRPA1ARKDM5BSRC | |
| SCHEMBL15341811 | 0.70 | TRPA1 (0.44) | APPTRPA1FAAHARKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011524864-A | — | — | 2011-09-08 | — | — | JP | claimed |
| WO-2009155017-A2 | NOVEL SUBSTITUTED AZABENZOXAZOLES | MERCK & CO., INC. (US) | 2009-12-23 | — | — | WO | claimed |