Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364060 | 0.86 | ALDH1A1 (0.39) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15234428 | 0.82 | FAAH (0.46) | ALDH1A1KMT2AMEN1TDP1TSHR | |
| SCHEMBL2550180 | 0.81 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7103835 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24444709 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9663210 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL45568 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11662265 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1276123 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13040556 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5354586-B2 | — | — | 2013-11-27 | — | — | JP | disclosed |
| JP-2011169888-A | METHOD OF MUTUAL SEPARATION BETWEEN Am, Cm AND Sm, Eu, Gd WITH CONCOMITANT USE OF N, N, N', N'-TETRAALKYL-3,6-DIOXAOCTANE-1,8-DIAMIDE (DOODA) AND TADGA (N,N,N',N'-TETRAALKYL-DIGLYCOL AMIDE) | JAPAN ATOMIC ENERGY AGENCY | 2011-09-01 | — | — | JP | disclosed |
| JP-2010271243-A | N,N,N',N'-TETRAALKYL-3,6-DIOXAOCTANE-1,8-DIAMIDE AND EXTRACTANT FOR SOLVENT-EXTRACTING ACTINIDE ELEMENT AND LANTHANIDE ELEMENT FROM HIGH LEVEL RADIOACTIVE WASTE LIQUID INCLUDING N,N,N',N'-TETRAALKYL-3,6-DIOXAOCTANE-1,8-DIAMIDE | JAPAN ATOMIC ENERGY AGENCY | 2010-12-02 | — | — | JP | disclosed |