SCHEMBL2641337

SCHEMBL2641337

C=CNC(=O)O[SiH]1CCCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1591636 0.77 ALDH1A1 (0.31)
SCHEMBL876640 0.73 ALDH1A1 (0.38)
SCHEMBL4405080 0.71
Methacrylic Acid SCHEMBL2065726 0.69 ALDH1A1 (0.34)
SCHEMBL11565517 0.67
SCHEMBL10882873 0.66
SCHEMBL21670826 0.65
SCHEMBL464844 0.64 ALDH1A1 (0.37)
SCHEMBL1331280 0.63
SCHEMBL512421 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197841-B2 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED (US) 2012-06-12 US claimed
JP-4732464-B2 2011-07-27 JP claimed
EP-2255228-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS Bausch & Lomb Incorporated (US) 2010-12-01 EP claimed
US-20100069522-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS HUMAX PHARMACEUTICAL S.A. (CO) 2010-03-18 US claimed
EP-1828813-B1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB (US) 2010-02-10 EP claimed
WO-2009117374-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS BAUSCH & LOMB INCORPORATED (US) 2009-09-24 WO claimed
WO-2008057104-A1 USE OF THERMAL REVERSIBLE ASSOCIATIONS FOR ENHANCED POLYMER INTERACTIONS BAUSCH & LOMB INCORPORATED (US) 2008-05-15 WO claimed
WO-2007149083-A1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB INCORPORATED (US) 2007-12-27 WO claimed
CN-101088029-A Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB (US) 2007-12-12 CN claimed
EP-1828813-A1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS Bausch & Lomb Incorporated (US) 2007-09-05 EP claimed
US-20070123602-A1 Use of thermal reversible associations for enhanced polymer interactions BAUSCH & LOMB INCORPORATED 2007-05-31 US claimed
US-20060275342-A1 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED 2006-12-07 US claimed
WO-2006068705-A1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB INCORPORATED (US) 2006-06-29 WO claimed
US-20060134169-A1 Polymerizable surfactants and their use as device forming comonomers SALIX PHARMACEUTICALS, INC. 2006-06-22 US claimed