SCHEMBL464844

SCHEMBL464844

CC(=O)OCCOC(C)=O.CC(=O)O[SiH]1CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 2/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
HTR1A P08908 1/20 0.33
CHRNB2 P17787 1/20 0.33
TBXA2R P21731 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CHRNA10 Q9GZZ6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2293082 0.89
SCHEMBL876640 0.78 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL11565517 0.75
Methacrylic Acid SCHEMBL2065726 0.74 ALDH1A1 (0.34) ALDH1A1TSHR
Cyclohexane SCHEMBL8927660 0.70 ALDH1A1 (0.59) ALDH1A1TSHRLMNAAPOBEC3AAPOBEC3G
SCHEMBL1591636 0.68 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL21670828 0.68
SCHEMBL64593 0.67 ALDH1A1 (0.68) ALDH1A1TSHRLMNAAPOBEC3AAPOBEC3G
SCHEMBL29446779 0.65 ALDH1A1 (0.65) ALDH1A1TSHRLMNAAPOBEC3AAPOBEC3G
Ammonia Solution, Strong SCHEMBL5679172 0.65 ALDH1A1 (0.65) ALDH1A1TSHRLMNAAPOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599559-B1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-30 EP disclosed
US-7157399-B2 Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components DOW GLOBAL TECHNOLOGIES INC. (US) 2007-01-02 US disclosed
EP-1599559-A1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-11-30 EP disclosed
US-6949603-B2 Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components DOW GLOBAL TECHNOLOGIES INC. (US) 2005-09-27 US disclosed
US-20040242812-A1 Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components DOW GLOBAL TECHNOLOGIES INC. 2004-12-02 US disclosed
US-6825298-B2 CATALYTIC FREE RADICAL ADDITION POLYMERIZATION OF OLEFINICALLY UNSATURATED MONOMOERS; CURING ADHESIVES; BONDING STRENGTH, HEAT RESISTANCE DOW GLOBAL TECHNOLOGIES INC. 2004-11-30 US disclosed
US-20040220363-A1 Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components DOW GLOBAL TECHNOLOGIES LLC 2004-11-04 US disclosed
US-20040210015-A1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS SONNENSCHEIN MARK F (US) 2004-10-21 US disclosed
WO-2004078871-A1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-09-16 WO disclosed
US-6777512-B1 MONOMERS, OLIGOMERS OR POLYMERS HAVING A SILOXANE BACKBONE CONTAINS ACRYLATE FUNCTIONAL MOIETIES DOW GLOBAL TECHNOLOGIES INC. 2004-08-17 US disclosed