Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26132977 | 0.81 | FNTA (0.49) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL26129570 | 0.81 | KDM4E (0.50) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9052803 | 0.78 | TSHR (0.58) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL30935665 | 0.77 | ALDH1A1 (0.47) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL26690191 | 0.77 | TSHR (0.44) | TSHRKDM4EALDH1A1HPGDGAA | |
| Oxalic Acid SCHEMBL27545073 | 0.75 | ALDH1A1 (0.54) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL4628672 | 0.74 | TSHR (0.60) | TSHRKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL10562029 | 0.72 | TSHR (0.57) | TSHRKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL367075 | 0.72 | TSHR (0.57) | TSHRALDH1A1HPGDGAAPOLB | |
| SCHEMBL30755337 | 0.72 | TSHR (0.57) | TSHRKDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183613-A2 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR INFLAMMATION | TACTOGEN INC (US) | 2023-09-28 | — | — | WO | disclosed |