SCHEMBL2641424

SCHEMBL2641424

CCCCCC1=C[C@@H](O)[C@@H](O)[C@@H](CO)O1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 5/20 0.33
SPHK2 Q9NRA0 4/20 0.33
SPHK1 Q9NYA1 3/20 0.33
PTPN1 P18031 1/20 0.33
OGA O60502 1/20 0.33
LMNA P02545 1/20 0.33
GBA1 P04062 1/20 0.33
SLC5A2 P31639 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2641449 1.00 PRKCA (0.33) PRKCASPHK2SPHK1PTPN1OGA
SCHEMBL30272593 0.98 PRKCA (0.35) PRKCASPHK2SPHK1PTPN1
SCHEMBL24256125 0.88 OGA (0.38) OGALMNAGBA1SLC5A2
SCHEMBL29377624 0.83 LMNA (0.38) OGALMNAGBA1SLC5A2
SCHEMBL31490979 0.83 LMNA (0.38) OGALMNAGBA1SLC5A2
SCHEMBL30910036 0.77 LMNA (0.39) LMNAGBA1
SCHEMBL1578387 0.72 CNR1 (0.32) OGALMNAGBA1
SCHEMBL9393831 0.71 GBA1 (0.43) PRKCASPHK2SPHK1OGALMNA
SCHEMBL2874569 0.70 GBA1 (0.42) PRKCALMNAGBA1
SCHEMBL15973936 0.70 LMNA (0.50) PRKCAPTPN1OGALMNAGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0654087-A4 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS. SCRIPPS RESEARCH INST (US) 1996-12-18 EP claimed
JP-H08500012-A 1996-01-09 JP claimed
EP-0654087-A1 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS THE SCRIPPS RESEARCH INSTITUTE (US) 1995-05-24 EP claimed
US-5403726-A Using beta galactosidase to form bond between a galactoside and a glucal THE SCRIPPS RESEARCH INSTITUTE (US) 1995-04-04 US claimed
WO-1994002624-A1 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS THE SCRIPPS RESEARCH INSTITUTE (US) 1994-02-03 WO claimed
EP-0654087-A4 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS. SCRIPPS RESEARCH INST (US) 1996-12-18 EP disclosed
EP-0654087-A1 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS THE SCRIPPS RESEARCH INSTITUTE (US) 1995-05-24 EP disclosed
US-5403726-A Using beta galactosidase to form bond between a galactoside and a glucal THE SCRIPPS RESEARCH INSTITUTE (US) 1995-04-04 US disclosed
WO-1994002624-A1 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS THE SCRIPPS RESEARCH INSTITUTE (US) 1994-02-03 WO disclosed