⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101954 | 0.74 | — | — | |
| SCHEMBL1420447 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL3104437 | 0.69 | — | — | |
| SCHEMBL11852700 | 0.67 | — | — | |
| SCHEMBL28123805 | 0.67 | TRPA1 (0.30) | — | |
| SCHEMBL9163817 | 0.67 | — | — | |
| SCHEMBL7580826 | 0.65 | — | — | |
| SCHEMBL11466998 | 0.64 | MEN1 (0.48) | — | |
| SCHEMBL11600974 | 0.64 | TSHR (0.42) | — | |
| SCHEMBL3404643 | 0.64 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4808610-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| US-20060204472-A1 | Multifunctional dendrimers and hyperbranched polymers as drug and gene delivery systems | PALEOS, CONSTANTINOS (GR) | 2006-09-14 | — | — | US | claimed |
| EP-1603967-A1 | MULTIFUNCTIONAL DENDRIMERS AND HYPERBRANCHED POLYMERS AS DRUG AND GENE DELIVERY SYSTEMS | National Center for Scientific Research Demokritos (GR) | 2005-12-14 | — | — | EP | claimed |
| WO-2004072153-A1 | MULTIFUNCTIONAL DENDRIMERS AND HYPERBRANCHED POLYMERS AS DRUG AND GENE DELIVERY SYSTEMS | NATIONAL CENTER FOR SCIENTIFIC RESEARCH 'DEMOKRITOS' (GR) | 2004-08-26 | — | — | WO | claimed |
| US-20060204472-A1 | Multifunctional dendrimers and hyperbranched polymers as drug and gene delivery systems | PALEOS, CONSTANTINOS (GR) | 2006-09-14 | — | — | US | disclosed |
| EP-1603967-A1 | MULTIFUNCTIONAL DENDRIMERS AND HYPERBRANCHED POLYMERS AS DRUG AND GENE DELIVERY SYSTEMS | National Center for Scientific Research Demokritos (GR) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004072153-A1 | MULTIFUNCTIONAL DENDRIMERS AND HYPERBRANCHED POLYMERS AS DRUG AND GENE DELIVERY SYSTEMS | NATIONAL CENTER FOR SCIENTIFIC RESEARCH 'DEMOKRITOS' (GR) | 2004-08-26 | — | — | WO | disclosed |