Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | GCK | P35557 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 1/20 | 0.43 |
| ▸ | ATP4B | P51164 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19598011 | 0.88 | STAT3 (0.55) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL31517975 | 0.83 | MAPK1 (0.50) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL26416014 | 0.83 | MAPT (0.50) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL26445880 | 0.83 | MAPT (0.50) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL23663288 | 0.83 | MAPT (0.54) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL23663332 | 0.83 | MAPT (0.50) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL10374510 | 0.83 | PDGFRB (0.54) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL24583106 | 0.83 | MAPT (0.50) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL25081934 | 0.81 | MAPT (0.64) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL16455676 | 0.81 | MAPT (0.47) | L3MBTL1MAPTMAPK1TDP1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780825-B2 | Thyroid hormone receptor agonists and use thereof | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780825-B2 | Thyroid hormone receptor agonists and use thereof | TSHR, THRA, THRB | L3MBTL1 4551/4885MAPT 112/4885MAPK1 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.