Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641674 | 0.90 | GPR119 (0.40) | GPR119 | |
| SCHEMBL1053663 | 0.81 | GPR119 (0.56) | GPR119 | |
| SCHEMBL1060164 | 0.80 | GPR119 (0.45) | GPR119 | |
| SCHEMBL12961780 | 0.79 | GPR119 (0.67) | GPR119 | |
| SCHEMBL1060873 | 0.78 | GPR119 (0.58) | GPR119 | |
| SCHEMBL1061381 | 0.78 | GPR119 (0.56) | GPR119 | |
| SCHEMBL1060691 | 0.77 | GPR119 (0.58) | GPR119 | |
| SCHEMBL1061052 | 0.75 | GPR119 (0.62) | GPR119 | |
| SCHEMBL1060759 | 0.75 | GPR119 (0.68) | GPR119 | |
| SCHEMBL1063121 | 0.75 | GPR119 (0.55) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438051-A1 | L- ( PIPERIDIN-4-YL) -PYRAZOLE DERIVATIVES AS GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010140092-A1 | L- ( PIPERIDIN-4-YL) -PYRAZOLE DERIVATIVES AS GPR 119 MODULATORS | PFIZER INC. (US) | 2010-12-09 | — | — | WO | disclosed |