Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335305 | 0.98 | NR3C2 (0.48) | NR3C2KMT2APKMBRD4MEN1 | |
| SCHEMBL26396444 | 0.96 | NR3C2 (0.46) | NR3C2KMT2APKMBRD4MEN1 | |
| SCHEMBL4043341 | 0.93 | KMT2A (0.43) | NR3C2KMT2APKMBRD4MEN1 | |
| SCHEMBL14335158 | 0.89 | KMT2A (0.54) | NR3C2KMT2A | |
| SCHEMBL22637693 | 0.86 | KMT2A (0.46) | NR3C2KMT2APKMBRD4MEN1 | |
| SCHEMBL29629510 | 0.85 | MEN1 (0.61) | NR3C2KMT2APKMMEN1ALDH1A1 | |
| SCHEMBL29629580 | 0.84 | OPRM1 (0.43) | NR3C2KMT2APKMMEN1ALDH1A1 | |
| SCHEMBL26690735 | 0.84 | KMT2A (0.45) | NR3C2KMT2APKMBRD4MEN1 | |
| SCHEMBL14335095 | 0.83 | GAA (0.62) | NR3C2KMT2APKMMEN1ALDH1A1 | |
| SCHEMBL30875144 | 0.83 | PARP1 (0.44) | NR3C2KMT2APKMMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |