Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.37 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125893 | 0.91 | OPRM1 (0.40) | OPRM1KDM4CTYK2PIK3CDPIK3R2 | |
| SCHEMBL29629564 | 0.88 | KDM4C (0.41) | OPRM1NR3C2KDM4CTYK2PIK3CD | |
| SCHEMBL26416283 | 0.84 | NR3C2 (0.49) | NR3C2PIK3CDKMT2APKMMEN1 | |
| SCHEMBL26396444 | 0.84 | NR3C2 (0.46) | OPRM1NR3C2PIK3CDPIK3CAKMT2A | |
| SCHEMBL14335305 | 0.83 | NR3C2 (0.48) | NR3C2PIK3CDKMT2APKMPOLB | |
| SCHEMBL4043341 | 0.81 | KMT2A (0.43) | NR3C2PIK3CDKMT2APKMMEN1 | |
| SCHEMBL22366382 | 0.79 | KDM4C (0.42) | OPRM1KDM4CPIK3CDPIK3R2PIK3CA | |
| SCHEMBL7876651 | 0.76 | TYK2 (0.41) | OPRM1KDM4CTYK2POLBSRC | |
| SCHEMBL30875144 | 0.75 | PARP1 (0.44) | NR3C2KMT2APKMMEN1ALDH1A1 | |
| SCHEMBL14335158 | 0.75 | KMT2A (0.54) | OPRM1NR3C2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169645-A1 | COMPOUNDS AS BRUTON TYROSINE KINASE INHIBITORS, PREPARATION METHODS AND MEDICAL APPLICATIONS THEREOF | Eternity Bioscience Inc. | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169645-A1 | COMPOUNDS AS BRUTON TYROSINE KINASE INHIBITORS, PREPARATION METHODS AND MEDICAL APPLICATIONS THEREOF | BTK, LYN, LCK | OPRM1 4024/4885NR3C2 866/4885KDM4C 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.