SCHEMBL26416447

SCHEMBL26416447

Cc1cc(NC(=O)c2ccc(C(=O)Nc3ccc(N)c(C)c3)cc2)ccc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.61
NPC1 O15118 8/20 0.61
KMT2A Q03164 5/20 0.61
MEN1 O00255 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
LMNA P02545 1/20 0.56
POLB P06746 1/20 0.56
PKM P14618 1/20 0.56
APEX1 P27695 1/20 0.56
MAPT P10636 4/20 0.56
FKBP5 Q13451 1/20 0.54
HDAC1 Q13547 2/20 0.52
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
CYP3A4 P08684 2/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50
RECQL P46063 1/20 0.50
HIF1A Q16665 1/20 0.50
NR1H4 Q96RI1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11493901 0.95 KMT2A (0.66) RAB9ANPC1KMT2AMEN1TDP1
SCHEMBL11594692 0.95 RAB9A (0.66) RAB9ANPC1KMT2AMEN1TDP1
SCHEMBL4658995 0.95 RAB9A (0.55) RAB9ANPC1KMT2AMEN1TDP1
SCHEMBL27888577 0.94 KMT2A (0.59) RAB9ANPC1KMT2AMEN1TDP1
SCHEMBL22025293 0.92 HDAC1 (0.64) RAB9ANPC1KMT2AMEN1TDP1
SCHEMBL3530325 0.92 KMT2A (0.69) RAB9ANPC1KMT2AMEN1POLB
SCHEMBL27905354 0.91 HDAC1 (0.58) RAB9ANPC1KMT2AMEN1LMNA
SCHEMBL17744810 0.89 NPC1 (0.58) RAB9ANPC1KMT2AMEN1TDP1
SCHEMBL31615133 0.89 RAB9A (0.50) RAB9ANPC1KMT2AMEN1TDP1
SCHEMBL22025298 0.88 KMT2A (0.59) RAB9ANPC1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230125363-A1 Polyamideimide Precursor, Polyamideimide Prepared Therefrom, and Polyamideimide Film Including the Same SK IE TECHNOLOGY CO., LTD. (KR) 2023-04-27 US disclosed