SCHEMBL26417023

SCHEMBL26417023

C=Cc1ccc(COC(=O)CCC(=O)OCc2ccc(C=C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 5/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
RAB9A P51151 2/20 0.39
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
GAA P10253 1/20 0.38
CA12 O43570 1/20 0.38
AKR1B10 O60218 1/20 0.38
AKR1B1 P15121 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8436340 0.93 MEN1 (0.43) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL26417024 0.93 KMT2A (0.41) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL8436882 0.93 ALDH1A1 (0.41) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL14732503 0.90 MEN1 (0.46) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL12231040 0.89 ALDH1A1 (0.43) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL24242072 0.87 KMT2A (0.40) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL8435267 0.87 HTT (0.42) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL14732562 0.87 TSHR (0.45) MEN1KMT2AALDH1A1MAPK1L3MBTL1
SCHEMBL2182981 0.86 CYP4F2 (0.39) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL2183399 0.86 FAAH (0.39) MEN1KMT2AMAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814450-B2 Polymeric solid support for oligonucleotide synthesis HONGENE BIOTECH CORPORATION (US) 2023-11-14 US disclosed
US-11814450-B2 Polymeric solid support for oligonucleotide synthesis HONGENE BIOTECH CORPORATION (US) 2023-11-14 US disclosed
US-20230130509-A1 POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-04-27 US disclosed
US-20230130509-A1 POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-04-27 US disclosed