Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.61 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26417363 | 0.92 | PTGER4 (0.72) | PTGER4PTGER2PHGDHKDM4EMAPT | |
| SCHEMBL26416555 | 0.92 | PTGER4 (0.62) | PTGER4PTGER2PHGDHCYP1A2CYP3A4 | |
| SCHEMBL24861972 | 0.92 | PTGER4 (0.61) | PTGER4PTGER2PHGDHPDE2ALMNA | |
| SCHEMBL24861973 | 0.92 | PTGER4 (0.61) | PTGER4PTGER2PHGDHPDE2ALMNA | |
| SCHEMBL24861807 | 0.90 | PTGER4 (0.62) | PTGER4PTGER2PHGDHPDE2AROCK2 | |
| SCHEMBL24861730 | 0.84 | PTGER4 (0.72) | PTGER4PTGER2PHGDHLMNA | |
| SCHEMBL24861806 | 0.84 | PTGER4 (0.72) | PTGER4PTGER2PHGDHLMNA | |
| SCHEMBL26417331 | 0.82 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861880 | 0.82 | PTGER4 (0.72) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861801 | 0.81 | PTGER4 (0.76) | PTGER4PTGER2PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125494-A1 | SYNTHESIS OF NOVEL EP4 ANTAGONIST AND USE IN CANCER AND INFLAMMATION | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230125494-A1 | SYNTHESIS OF NOVEL EP4 ANTAGONIST AND USE IN CANCER AND INFLAMMATION | PTGER4, PTGER3, PTGER2 | PTGER4 1/4885PTGER2 3/4885PHGDH 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.